教室業績


著書

1. 八木橋操六: 臨床医のための糖尿病病理, 診断と治療社, 東京, 2004

2. 和田龍一: カラーアトラス 基礎組織病理学 第4版, 今井大, 山川光徳監訳, 西村書店, 東京, 2004

3. 松岡健平, 堀田饒, 八木橋操六編, 糖尿病性神経障害, 現代医療社, 東京, 2001

4. 澤井高志, 内藤眞, 名倉宏, 八木橋操六編, エッセンシャル病理学(第5版), 医歯薬出版, 東京, 2000

5. Yagihashi S, Kachi T, Wakui M (editors), Dynamic Cells, Cell bioloby of the 21st Century. Elsevier, Amsterdam, 1998

 

原著論文

Wada R, Yagihashi S: Nitric oxide generation and poly(ADP Ribose) polymerase activation precede beta-cell death in rats with a single high-dose injection of streptozotocin. Virchows Archiv 444:375-382, 2004

Maruya S, Kurotaki H, Wada R, Saku T, Shinkawa H, Yagihashi S: Promoter methylation and protein expression of the E-cadherin gene in the clinicopathologic assessment of adenoid cystic carcinoma. Mod Pathol, 2004

 

Yamagishi S, Uehara K, Otsuki S, Yagihashi S: Differential influence of increased polyol pathway on protein kinase C expressions between endoneurial and epineurial tissues in diabetic mice. J Neurochem 87: 497-507, 2003

Wada R, Itabashi C, Nakayama Y, Ono Y, Murakami C, Yagihashi S: Chronic granulomatous pleuritis caused by Nocardia. PCR-based diagnosis by Nocardial 16S rDNA in pathological specimens. J Clin Pathol 56:965-968, 2003

Maruya S, Kurotaki H, Shimoyama N, Kaimori M, Shinkawa H, Yagihashi S: Expression of p16 protein and hypermethylation status of its promoter gene in adenoid cystic carcinoma of the head and neck. ORL 65:26-32, 2003

Shikama Y, Osawa T, Yagihashi N, Kurotaki H, Yagihashi S: Neuroendocrine differentiation in hyalinizing trabecular tumor of the thyroid. Virchows Arch 443:792-796, 2003

Sugimoto K, Baba M, Suda T, Yasujima M, Yagihashi S: Peripheral neuropathy and microangiopathy in rats with insulinoma: association with chronic hyperinsulinemia. Diabetes Metab Res Rev 19:392-400, 2003

Suga S, Nakano K, Takeo T, Osanai T, Ogawa Y, Yagihashi S, Kanno T, Wakui M: Masked excitatory action of noradrenaline on rat islet beta-cells via activation of phospholipase C. Pflugers Arch 447:337-44, 2003

Ruderman NB, Cacicedo JM, Itani S, Yagihashi N, Saha AK, Ye JM, Chen K, Zou M, Carling D, Boden G, Cohen RA, Keaney J, Kraegen EW, Ido Y: Malonyl-CoA and AMP-activated protein kinase (AMPK): possible links between insulin resistance in muscle and early endothelial cell damage in diabetes. Biochem Soc Trans 2003, 31(Pt 1):202-6

Yamashita T, Hashiramoto A, Haluzik M, Mizukami H, Beck S, Norton A, Kono M, Tsuji S, Daniotti JL, Werth N, Sandhoff R, Sandhoff K, Proia RL: Enhanced insulin sensitivity in mice lacking ganglioside GM3. Proc Natl Acad Sci USA 100:3445-9, 2003

板橋智映子, 和田龍一, 蝦名義仁, 横濱弘美, 八木橋操六: 内分泌異常を伴った血管内大細胞型Bリンパ腫の1剖検例. 癌の臨床, 49:55-59, 2003

矢嶋信久, 黒滝日出一, 西澤雄介, 伊藤卓, 横山昌樹, 石川惟愛, 八木橋操六: Sister Mary Joseph's Nodule (転移性臍癌)の3自検例とわが国における報告例からの文献的考察. 癌の臨床 49:711-716, 2003

成田純子, 和田龍一, 八木橋操六: 乳癌病理標本におけるHER2の免疫染色法の検討. 青臨技会誌 27:34-37, 2003

 

Sakuraba H, Mizukami H, Yagihashi N, Wada R, Hanyu C, Yagihashi S: Reduced beta-cell mass and expression of oxidative stress-related DNA damage in the islet of Japanese Type II diabetic patients. Diabetologia 45:85-96, 2002

Wada R, Ebina Y, Kurotaki H, Yagihashi S: Intracytoplasmic immunoglobulin crystals in follicular lymphoma. Human Pathology 33:1141-1144, 2002

Maruya S, Kurotaki H, Shimoyama N, Kaimori M, Sinkawa H, Yagihashi S: Expression of p16 protein and hypermethylation status of its promoter gene in adenoid cystic carcinoma of the head and neck. ORL 64: 2002

Mizukami H, Mi Y, Wada R, Kono M, Yamashita T, Liu Y, Werth N, Sandhoff R, Sandhoff K and Proia RL: Systemic inflammation in glucocerebrosidase-deficient mice with minimal glucosylceramide storage. J Clin Invest 109:1215-1221, 2002

Imaizumi T, Kumagai M, Sasaki N, Kurotaki H, Mori F, Seki M, Nishi N, Fujimoto K, Tanji K, Shibata T, Tamo W, Matsumiya T, Yoshida H, Cui XF, Takanashi S, Hanada K, Okumura K, Yagihashi S, Wakabayashi K, Hirashima M, and Satoh K: Interferon-g stimulates the expression of galectin-9 in cultured human endothelial cells. J Leukoc Biol 72:492-502, 2002

Mori F, Hayashi S, Yamagishi S, Yoshimoto M, Yagihashi S, Takahashi H, Wakabayashi S: Pick's disease: alpha- and beta-synuclein-immunoreactive Pick bodies in the dentate gyrus. Acta Neuropathol 104:455-61, 2002

Kitahara Y, Miura K, Takesue K, Mine T, Wada R, Uchida Y, Ito S, Yagihashi S: Decreased blood glucose excursion by nateglinide ameliorated neuropathic changes in Goto-Kakizaki rats, and animal model of non-obese type 2 diabetes. Metabolism 51:1452-1457, 2002

松本一仁, 池崎福治, 柿崎寛, 吉岡治彦, 八木橋操六: 肩胛部に発生した褐色脂肪腫の1例. 日本臨床細胞学会雑誌 41:427-432, 2002

 

Yagihashi S, Yamagishi S, Wada R, Baba M, Hohman TC, Yabe-Nishimura C, Kokai Y: Neuropathy in diabetic mice overexpressing human aldose reductase and effects of aldose reductase inhibitor. Brain 124:2448-2458, 2001

Wada R, Nishizawa Y, Yagihashi N, Takeuchi M, Ishikawa Y, Yasumura K, Nakano M, Yagihashi S: Effects of OPB-9195, anti-glycation agent, on experimental diabetic neuropathy. Eur J Clin Invest 31:513-20, 2001

Wada R, Kawamura C, Inoue S, Watanabe K, Kaimori M, Yagihashi S: Granulomatous colitis associated with botryomycosis of Propionibacterium acnes. Arch Pathol Lab Med 125:1491-1493, 2001

Kasajima H, Yamagishi S, Sugai S, Yagihashi N, Yagihashi S: Enhanced in situ expression of aldose reductase in diabetic patients. Virchows Arch 439:46-54, 2001

Maruya S, Kurotaki H, Fujita S, Sariishi T, Shinkawa H, Yagihashi S: Primary chondrosarcoma arising in the parotid gland. ORL 63:110-113, 2001

Matsumoto K, Kakizaki H, Yagihashi N, Yagihashi S: Malignant glomus tumor in the branchial muscle of a 16-year-old girl. Pathology Int 51:729-734, 2001

Tsuji T, Ishiguro Y, Nakui Y, Murata Y, Munakata A, Onozuka N, Fukui K, Suzuki S, Yamagishi S: A case of dissecting aortic aneurysm with cystic medial necrosis in systemic lupus erythematosus. Mod Rheumatol 11:238-241, 2001

Shibata Y, Ueda T, Seki H, Yagihashi N: Gastrointestinal stromal tumour of the rectum. Eur J Gastro Hepa 13:283-286, 2001

Seki H, Ueda T, Shibata Y, Sato Y, Yagihashi N: Solitary thyroid metastasis of renal clear cell carcinoma: report of a case. Surg Today 31:225-229, 2001

小山博美, 市川千佳子, 渡部万美, 大澤忠治, 八木橋法登, 黒滝日出一, 八木橋操六: 乳腺Matrix-producing carcinoma の1例. 日本臨床細胞学会秋田県支部会誌 7:25-28, 2001

松本一仁,柿崎寛,佐々木幸雄,八木橋法登: 股関節周囲の筋肉内に発生したlipomatous hemangiopericytomaの一例. 診断病理 18:189-193, 2001

四釜育与, 成田淳一, 伊藤博之, 八木橋信夫, 黒滝日出一, 八木橋操六: 背景病変に慢性甲状腺炎を伴った甲状腺悪性リンパ腫の一例. 日本臨床細胞学会青森県支部会報 18:9-13, 2001

 

Kurotaki H, Yagihashi S: Apoptosis, bcl-2 expression and p53 accumulation in myelodysplastic syndrome (MDS), MDS-derived acute myelogenous leukemia (AML) and de novo AML. Proc Jpn Soc Pathol 89:260, 2000

Yagihashi N, Kasajima H, Sugai S, Matsumoto K, Ebina Y, Morita T, Murakami T, Yagihashi S: Increased in situ expression of nitric oxide synthase in human colorectal cancer. Virchows Arch 436:109-114, 2000

Wada R, Tifft C, Proia RL: Microglial activation precedes neurodegeneration in Sandhoff disease and is suppressed after bone marrow transplantation. Proc Natl Acad Sci 97:10954-10959, 2000

Koyama M, Wada R, Mizukami H, Sakuraba H, Odaka H, Ikeda H, Yagihashi S: Inhibition of progressive reduction of islet beta-cell mass in spontaneously diabetic Goto-Kakizaki rats by alpha-glucosidase inhibitor. Metabolism 49:347-352, 2000

Liu Y, Wada R, Yamashita T, Yide M, Deng C-X, Hobson JP, Rosenfeldt HM, Nava VE, Chae SS, Lee MJ, Liu CH, Hla T, Spiegel S, Proia RL: Edg-1, the G protein-coupled receptor for sphingosine-l-phosphate, is essential for vascular maturation. J Clin Invest 106:951-961, 2000

Kato N, Mizuno K, Makino M, Suzuki T, Yagihashi S: Effects of 15-month aldose reductase inhibition with fidarestat on the experimental diabetic neuropathy in rats. Diabetes Research and Clinical Practice 50:77-85, 2000

松本一仁, 池崎福治, 宮本誠一, 佐々木幸雄, 八木橋操六: 細胞異型の目立った成長ホルモン産生巨大化下垂体腺腫の1例. 日本臨床細胞学会雑誌39:199-203, 2000

長沼孝雄, 中村洋子, 大高昌子, 黒滝日出一, 八木橋操六, 鎌田義正, 松本一仁: 甲状腺硝子化索状腺腫の1例. 日本臨床細胞学会青森県支部会報 17:11-15, 2000

四釜育与, 原田治, 成田淳一, 八木橋信夫, 黒滝日出一, 八木橋操六: 乳腺原発リンパ腫の一例. 日本臨床細胞学会青森県支部会報 17:3-6, 2000


病理学第一講座トップ

弘前大学医学部医学科トップ  弘前大学医学部医学科教育研究組織一覧