| 抄読会順番表（毎週火曜日午前８時３０分より） 注：日時が４月１０より変更になっています。 |
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各論文はPubMedのabstractにリンクを張っています。 |
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| 月日 |
当番 |
紹介論文 |
|
| ２００１年 |
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|
| 1月15日 |
瀬谷 |
Regulation of
Cloned Cardiac L-type Calcium Channels by cGMP-dependent Protein Kinase.
Jiang, L.H. et al. J. Biol. Chem. 275, 6135-6143 (2000) |
|
|
| 1月22日 |
|
Molecular
Mechanism of Fibronectin Gene Activation by Cyclic Stretch in Vascular Smooth
Muscle Cells. Tamura, K., Chen,
Y.E., Lopez-Ilasaca, M., Daviet, L., Tamura, N., Ishigami, T., Akishita, M.,
Takasaki, I., Tokita, Y., Pratt, R.E., Horiuchi, M., Dzau, V., and Umemura,
S. J. Biol. Chem. 275,
34619-34627 (2000) |
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|
| 1月29日 |
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|
| 2月5日 |
丹野 |
Mechanical
stretch stimulates growth of vascular smooth muscle cells via epidermal
growth factor receptor. Iwasaki K, et al. Am. J. Physiol. 278, H521-H529
(2000) |
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|
| 2月12日 |
祭日 |
|
|
|
| 2月19日 |
岩崎 |
Effect
of extracellular calcium on the gene expression of bone morphogenetic
protein-2 and -4 of normal human bone cells. Nakade, O. et al. Journal of Bone and
Mineral Metabolism 19, 13-19 (2001) |
|
|
| 2月26日 |
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|
| 3月5日 |
木村 |
|
|
|
| 4月10日 |
小林 |
Verapamil prevents
stretch-induced shortening of atrial effective refractory period in
langendorff-perfused rabbit heart. Zarse, M. et al. J Cardiovasc.
Electrophysiol. 12, 85-92 (2001) |
|
|
| 4月17日 |
橋本 |
Calcium-channel
activation and matrix protein upregulation in bone cells in response to
mechanical strain. Walker, L.M.
et al. J. Cell Biochem. 79, 648-61 (2000) |
|
|
| 4月24日 |
瀬谷 |
Dual
modulation of cell survival and cell death by beta(2)-adrenergic signaling in
adult mouse cardiac myocytes. Zhu, W.Z. et al. Proc. Natl. Acad. Sci. USA 98,
1607-12 (2001) |
|
| 5月1日 |
古川 |
Characterization
and gene expression of high conductance calcium-activated potassium channels
displaying mechanosensitivity in human odontoblasts. Allard, B. et al., J.
Biol. Chem. 275, 25556-25561 (2000) |
|
| 5月8日 |
岩崎 |
Tensile
stress induces bone morphogenetic protein 4 in preosteoblastic and
fibroblastic cells, which later differentiate into osteoblasts leading to
osteogenesis in the mouse calvariae in organ culture. Ikegame, M. et al. J.
Bone Miner. Res. 16, 24-32 (2001) |
|
| 5月15日 |
木村 |
Functional
roles of cardiac and vascular ATP-sensitive potassium channels clarified by
Kir6.2-knockout mice. Suzuki, M.
et al. Circ. Res. 88, 570-577
(2001) |
|
|
| 5月22日 |
小林 |
Role
of the Na(+)/H(+) exchanger in short-term atrial electrophysiological
remodeling. Jayachandran JV et al. Circulation 101, 1861-6 (2000) |
|
| 5月29日 |
橋本 |
Pathophysiological
and protective roles of mitochondrial ion channels. O'Rourke B. J Physiol
2000, 529, 23-36 (2000) |
|
| 6月5日 |
瀬谷 |
Complete
heart block and sudden death in mice overexpressing calreticulin.
Nakamura, K. et al. J. Clin.
Invest., 107, 1245-53 |
|
| 6月12日 |
古川 |
Leptin
enhances the calcification of vascular cells : artery wall as a target of
leptin. Parhami, F. et al. Circ.
Res., 88, 954-60 (2001) |
|
| 6月19日 |
岩崎 |
Cbfa1
Contributes to the Osteoblast-specific Expression of type I collagen
Genes. Kern, B. et al. J. Biol. Chem. 276, 7101-7 (2001) |
|
| 6月26日 |
木村 |
Long-chain
acyl-coenzyme A esters and fatty acids directly link metabolism to K(ATP)
channels in the heart. Liu, G.X.
et al. Circ. Res. 88, 918-24
(2001) |
|
| 7月3日 |
小林 |
Angiotensin
II inhibits rat arterial KATP channels by inhibiting steady-state protein
kinase A activity and activating protein kinase Ce. Hayabuchi, Y. et al. J. Physiol., 530, 193-205 (2001) |
|
| 7月10日 |
橋本 |
Expression
of ryanodine receptor type 3 and TRP channels in endothelial cells:
comparison of in situ and cultured human endothelial cells. Kohler, R. et al.
Cardiovasc Res, 51, 160-168 (2001) |
|
| 7月17日 |
瀬谷 |
Effects
of In Vivo Nitroglycerin Treatment on Activity and Expression of the Guanylyl
Cyclase and cGMP-Dependent Protein Kinase and Their Downstream Target
Vasodilator-Stimulated Phosphoprotein in Aorta. Mulsch, A. et al. Circulation, 103, 2188-94. |
|
| 7月24日 |
古川 |
Tumor
necrosis factor-alpha induces fibronectin synthesis in coronary artery smooth
muscle cells by a nitric oxide-dependent posttranscriptional mechanism.
O'Blenes C.A. et al. Circ. Res. 89, 26-32 (2001) |
|
| 9月11日 |
岩崎 |
|
|
|
| 9月18日 |
木村 |
Upregulation of Functional
beta3-adrenergic receptor in the Failing Canine Myocardium. Cheng H.J. et al.
Circ. Res. 89, 599-606 (2001) |
|
| 9月25日 |
小林 |
Regulation
of angiotensin II receptor subtypes during atrial fibrillation in humans.
Goette, A. et al. Circulation, 101, 2678-81 (2000) |
|
| 10月1日 |
大和田 |
Altered
stoichiometry of FKBP12.6 versus ryanodine receptor as a cause of abnormal
Ca(2+) leak through ryanodine receptor in heart failure. Yano, M. et al.
Circulation 102, 2131-6 (2000). |
|
| 10月15日 |
橋本 |
Essential
role for extracellular Ca(2+) in JNK activation by mechanical stretch in
bladder smooth muscle cells. Kushida, N. et al. Am J Physiol Cell Physiol
281, C1165-72 (2001) |
|
| 10月22日 |
瀬谷 |
Calcineurin
pathway is required for endothelin-1-mediated protection against oxidant
stress-induced apoptosis in cardiac myocytes. Kakita, T., Circ. Res. 88, 1239-46
(2001) |
|
| 11月5日 |
古川 |
Characterization
of stretch-activated cation current in coronary smooth muscle cells. Wu X,
Davis MJ. Am J Physiol Heart Circ Physiol 280, H1751-61 (2001) |
|
| 11月12日 |
岩崎 |
MAPK
pathways activate and phosphorylate the osteoblast-specific transcription
factor, Cbfa1. Xiao, G. et al. J
Biol Chem 275, 4453-9 (2000) |
|
| 11月19日 |
木村 |
Activation
of protein kinase A modulates trafficking of the human cardiac sodium channel
in Xenopus oocytes. Zhou, J. et al. Circ. Res. 87, 33-8 (2000) |
|
| 11月26日 |
小林 |
Transcriptional
and translational regulation of calpain in the rat heart after myocardial
infarction--effects of AT(1) and AT(2) receptor antagonists and ACE
inhibitor. Sandmann, S. et al. Br. J. Pharmacol., 132, 767-77 (2001) |
|
| 12月3日 |
大和田 |
Decreased
sarcoplasmic reticulum calcium content is responsible for defective
excitation-contraction coupling in canine heart failure. Hobai, I.A.,
O'Rourke, B. Circulation 103, 1577-84 (2001) |
|
| 12月10日 |
橋本 |
Protective
role of ATP-sensitive potassium channels in hypoxia-induced generalized
seizure. Yamada, K. et al. Science 292, 1543-6 (2001) |
|
| 12月17日 |
瀬谷 |
Anti-apoptotic
Effect of cGMP in Cultured Astrocytes. inhibition by cGMP-dependent protein
kinase of mitochondrial permeable transition pore. Takuma, K. et al. J. Biol. Chem. 276,
48093-48099 (2001) |
|
| ２００２年 |
|
|
| 1月21日 |
岩崎 |
Physical
shock wave mediates membrane hyperpolarization and Ras activation for
osteogenesis in human bone marrow stromal cells. Wang FS et al. Biochem.
Biophys. Res. Commun. 287, 648-655 |
|
| 1月28日 |
古川 |
Extracellular
nucleotides induce arterial smooth muscle cell migration via osteopontin.
Chaulet, H. et al. Circ Res 89, 772-778 (2001) |
|
| 2月4日 |
木村 |
Nitric
oxide modulates cardiac Na(+) channel via protein kinase A and protein kinase
G. Ahmmed, G.U. et al. Circ Res 89, 1005-13 (2001) |
|
| 2月11日 |
|
建国記念日でお休み |
|
| 2月18日 |
小林 |
beta-adrenergic
receptor blockers restore cardiac calcium release channel (ryanodine
receptor) structure and function in heart failure. Reiken, S. et al.
Circulation 104, 2843-2848 (2001) |
|
| 2月25日 |
大和田 |
T-type
calcium currents in rat cardiomyocytes during postnatal development:
contribution to hormone secretion. Leuranguer, V. et al. Am. J. Physiol.
Heart Circ. Physiol. 279, H2540-8 (2000) |
|
| 3月4日 |
橋本 |
Simvastatin
promotes osteoblast differentiation and mineralization in MC3T3-E1 cells. |
|
| |
橋本 |
Pitavastatin
enhanced BMP-2 and osteocalcin expression by inhibition of Rho-associated
kinase in human osteoblasts. Ohnaka, K. et al. Biochem. Biophys. Res. Commun.
287, 337-42 (2001) |
|
| 3月11日 |
瀬谷 |
Identification
of a neuronal nitric oxide synthase in isolated cardiac mitochondria using
electrochemical detection. Kanai,
A.J. et al. Proc. Natl. Acad.
Sci. USA, 98, 14126-31 (2001) |
|
| 4月15日 |
古川 |
Smooth
muscle cell phenotypic transition associated with calcification: upregulation
of Cbfa1 and downregulation of smooth muscle lineage markers. Steitz, S.A. et al. |
|
| 4月22日 |
岩崎 |
Bone
morphogenetic proteins, extracellular matrix, and mitogen-activated protein
kinase signaling pathways are required for osteoblast-specific gene
expression and differentiation in MC3T3-E1 cells. Xiao, G. et al. J. Bone
Miner. Res. 17, 101-110 (2002) |
|
| 5月13日 |
木村 |
A
calcium sensor in the sodium channel modulates cardiac excitability. Tan,
H.L. et al. Nature 415, 442-447 |
|
| 5月20日 |
小林 |
Altered
expression of ADAMs (A Disintegrin And Metalloproteinase) in fibrillating
human atria. Arndt, M. et al.
Circulation 105, 720-5 (2002) |
|
| 5月27日 |
大和田 |
Molecular
basis of downregulation of G-protein-coupled inward rectifying K(+) current
(I(K,ACh) in chronic human atrial fibrillation: decrease in GIRK4 mRNA
correlates with reduced I(K,ACh) and muscarinic receptor-mediated shortening
of action potentials. Dobrev,D. et al. Circulation 104, 2551-2557 (2001) |
|
| 6月10日 |
足利 |
Consequences
of atrial tachycardia-induced remodeling depend on the preexisting atrial
substrate. Shinagawa, K. et al.
Circulation 105, 251-257 (2002) |
|
| 6月17日 |
橋本 |
Expression
of Na(+)/Ca(2+) exchanger isoforms (NCX1 and NCX3) and plasma membrane Ca(2+)
ATPase during osteoblast differentiation. Stains, J.P. et al. J. Cell. Biochem.
84, 625-635 (2002) |
|
| 6月24日 |
瀬谷 |
Rapid
regulation of steroidogenesis by mitochondrial protein import. Bose, H. et
al. Nature 417, 87-91 (2002) |
|
| 7月22日 |
古川 |
Integrins
play a critical role in mechanical stress-induced p38 MAPK
activation. Aikawa, R. et al. Hypertension 39, 233-8 (2002) |
|
| 9月30日 |
岩崎 |
The
bone-specific transcriptional regulator Cbfa1 is a target of mechanical
signals in osteoblastic cells. Ziros, P.G. et al. J. Biol. Chem. 277,
23934-41 (2002) |
|
| 10月7日 |
木村 |
Role
of heteromultimers in the generation of myocardial transient outward K+
currents. Guo, W. Circ. Res. 90,
586-93 (2002) |
|
| 10月21日 |
足利 |
Ionic
and cellular basis for the predominance of the Brugada syndrome phenotype in
males. Di Diego, J.M. et al. Circulation 106, 2004-2011 (2002) |
|
| 10月28日 |
小林 |
Consequences
of atrial tachycardia-induced remodeling depend on the preexisting atrial
substrate. Shinagawa, K. et al. Circulation, 105, 251-257 (2002). |
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| |
|
Dynamic
nature of atrial fibrillation substrate during development and reversal of
heart failure in dogs. Shinagawa, K. et al. Circulation, 105, 2672-2678
(2002) |
|
| 11月11日 |
大和田 |
Human
cardiac inwardly-rectifying K+ channel Kir(2.1b) is inhibited by direct
protein kinase C-dependent regulation in human isolated cardiomyocytes and in
an expression system. Karle, C.A. et al. Circulation 106, 1493-1499 (2002) |
|
| 11月18日 |
橋本 |
The
mechanism of phenylephrine-mediated [Ca(2+)](i) oscillations underlying tonic
contraction in the rabbit inferior vena cava. Lee, C.H. et al. J. Physiol.
534, 641-650 (2001) |
|
| 11月25日 |
瀬谷 |
|
|
| 12月2日 |
古川 |
Bone
morphogenetic protein 2 induces cyclo-oxygenase 2 in osteoblasts via a Cbfal
binding site: role in effects of bone morphogenetic protein 2 in vitro and in
vivo. Chikazu, D. et al. J. Bone Miner. Res. 17, 1430-40 （2002） |
|
| 2003年 |
|
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|
| 1月20日 |
岩崎 |
Human
autologous culture expanded bone marrow mesenchymal cell transplantation for
repair of cartilage defects in osteoarthritic knees. Wakitani, S. et al. Osteoarthritis and
Cartilage 10. 199-206 (2002) |
|
| 1月27日 |
小林 |
Downregulation
of endocardial nitric oxide synthase expression and nitric oxide production
in atrial fibrillation: potential mechanisms for atrial thrombosis and
stroke. Cai, H. et al. Circulation 106, 2854-2858 (2002) |
|
| 2月3日 |
木村 |
Thrombin
facilitation of voltage-gated sodium channel activation in human
cardiomyocytes: implications for ischemic sodium loading. Pinet, C. et al.,
Circulation 106, 2098-103 (2002) |
|
| 2月10日 |
足利 |
Chronic
amiodarone-induced inhibition of the Na(+)-K(+) pump in rabbit cardiac
myocytes is thyroid-dependent: comparison with dronedarone. Pitt, A.D. et
al., Cardiovasc. Res. 57, 101-8 (2003) |
|
| 2月17日 |
大和田 |
Depressed
transient outward potassium current density in catecholamine-depleted rat
ventricular myocytes. Bru-Mercier, G. et al. Am. J. Physiol. Heart Circ.
Physiol. 282, H1237-47 (2002) |
|
| 2月24日 |
橋本 |
A
role for phosphorylation of inositol 1,4,5-trisphosphate receptors in
defining calcium signals induced by Peptide agonists in pancreatic acinar
cells. Straub et al. J. Biol. Chem. 277, 31949-31956 (2002) |
|
| 3月3日 |
古川 |
Ca2+-stimulated
Ca2+ oscillations produced by the Ca2+-sensing receptor require negative
feedback by protein kinase C.
Young, S.H. et al. J. Biol. Chem. 277, 46871-46876 (2002) |
|
| 3月10日 |
瀬谷 |
Nitric
oxide promotes intracellular calcium release from mitochondria in striatal
neurons. Horn, T.F. et al., FASEB J. 16, 1611-1622 (2002) |
|
| 4月14日 |
木村 |
Long
QT syndrome, Brugada syndrome, and conduction system disease are linked to a
single sodium channel mutation.
Grant, A.O. et al. J. Clin. Invest.110,1075-1077 (2002) |
|
| 5月12日 |
小林 |
Effects
of antiarrhythmic drugs on fibrillation in the remodeled atrium: insights
into the mechanism of the superior efficacy of amiodarone. Shinagawa, K. et
al. Circulation 107, 1440-1446
(2003) |
|
| 5月19日 |
足利 |
Yamashita,
T. et al. Circadian variation of cardiac K+ channel gene expression. |
|
| 5月26日 |
橋本 |
Adrenergic
regulation of clock gene expression in mouse liver. Terazono, H. et al. Proc Natl Acad Sci
USA 2003 (epub ahead of print) |
|
| 6月2日 |
瀬谷 |
Nisoli,
E. et al. Mitochondrial biogenesis in mammals: the role of endogenous nitric
oxide. Science 299, 838-839 (2003) |
|
| 6月9日 |
古川 |
Grote,
K., Mechanical Stretch Enhances mRNA Expression and Proenzyme Release of
Matrix Metalloproteinase-2 (MMP-2) via NAD(P)H Oxidase-Derived Reactive
Oxygen Species. Circ Res. 2003 (Epub ahead of print) |
|
| 6月23日 |
木村 |
Decreasing
cellular hydrogen peroxide with catalase mimics the effects of hypoxia on the
sensitivity of the L-type Ca2+ channel to beta-adrenergic receptor
stimulation in cardiac myocytes. Hool, L.C. and Arthur, P.G. Circ Res, 91,
601-9 (2002) |
|
| 7月7日 |
小林 |
Atrial
ischemia promotes atrial fibrillation in dogs. Sinno, H. et al. Circulation
107:1930-1936 (2003) |
|
| 7月14日 |
足利 |
Widening
of the excitable gap and enlargement of the core of reentry during atrial
fibrillation with a pure sodium channel blocker in canine atria. Kawase, A.
et al. Circulation 107:905-910 (2003) |
|
| 9月22日 |
瀬谷 |
Nitric
oxide prevents 6-hydroxydopamine-induced apoptosis in PC12 cells through
cGMP-dependent PI3 kinase/Akt activation. Ha KS et al. FASEB J.
2003;17:1036-47 |
|
| 9月29日 |
全員 |
Progress Seminar |
|
| 10月6日 |
古川 |
Collett,
G. et al. Receptor tyrosine kinase Axl modulates the osteogenic
differentiation of pericytes. Circ Res.
92, 1123-1129 (2003) |
|
| 10月20日 |
沢田 |
Release
and interconversion of P2 receptor agonists by human osteoblast-like cells.
Buckley, K.A. et al. FASEB J. 17, 1401-1410 (2003). |
|
| 10月27日 |
木村 |
FKBP12.6-mediated
stabilization of calcium-release channel (ryanodine receptor) as a novel
therapeutic strategy against heart failure. Yano, M. et al. Circulation
2003;107:477-484 |
|
| 11月10日 |
足利 |
Fibrosis
of the left atria during progression of heart failure is associated with
increased matrix metalloproteinases in the rat. Boixel, C. et al. J. Am.
Coll. Cardiol. 2003;42:336-44. |
|
| 12月1日 |
瀬谷 |
Concentration
dependent mitochondrial effect of amiodarone. Varbiro, G. et al. Biochem.
Pharmacol. 65:1115-28 (2003) |
|
| 12月8日 |
古川 |
Downregulation
of the BK channel beta1 subunit in genetic hypertension. Amberg, G.C. and
Santana L.F. Circ. Res. 93, 965-971 (2003). |
|
| 12月15日 |
沢田利匡 |
Extracellular
ATP stimulates the early growth response protein 1 (Egr-1) via a protein
kinase C-dependent pathway in the human osteoblastic HOBIT cell line. Pines,
A. et al. Biochem. J. 373:815-824 (2003) |
|
| 12月22日 |
全員 |
Progress Seminar |
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|
| 2004年 |
|
|
| 1月19日 |
足利 |
Inflammation
as a risk factor for atrial fibrillation. Aviles, R.J. et al. Circulation.
2003;108: 3006-3010 |
|
| 1月26日 |
小林 |
Effect
of shear stress on asymmetric dimethylarginine release from vascular
endothelial cells. Osanai, T. et al. Hypertension 2003;42:985-990. |
|
| 2月2日 |
瀬谷 |
Schild,
L. et al. Nitric oxide produced in rat liver mitochondria causes oxidative
stress and impairment of respiration after transient hypoxia. FASEB J.
2003;17:2194-2201 |
|
| 2月9日 |
古川 |
Tanaka,
K. et al. Diverse contribution of bone marrow cells to neointimal hyperplasia
after mechanical vascular injuries. Circ Res. 2003;93:783-790 |
|
| 2月16日 |
沢田 |
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| 2月23日 |
足利 |
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| 3月1日 |
該当者 |
学会発表練習 |
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