Featured Publication

L-Glucose: Another Path to Cancer Cells.

Ono, K., Takigawa, S., and Yamada, K.  Cancers 12: 850 (2020)

 
     
  Currently Ongoing Brain Project Currently Ongoing Imaging Project
  Neurotransmitter-induced Gliotransmitter Release and Glial Heterogeneity Imaging Glucose Uptake into Normalanl Cancer Cells by Fluorescent Glucose Analogues
 
 
Recent publications from our lab
Ogawa, T., Sasaki, A., Ono, K., Ohshika, S., Ishibashi, Y., Yamada, K. Uptake of fluorescent D- and L-glucose analogues, 2-NBDG and 2-NBDLG, into human osteosarcoma U2OS cells in a phloretin-inhibitable manner. Human Cell 34: 634-643 (2021)
Ono, K., Takigawa, S., Yamada, K. L-Glucose: Another Path to Cancer Cells. Cancers 12: 850 (2020)
Shibasaki, K., Yamada, K., Miwa, H., Yanagawa, Y., Suzuki, M., Tominaga, M., Ishizaki, Y. Temperature elevation in epileptogenic foci exacerbates epileptic discharge through TRPV4 activation. Lab. Invest. 100: 274-284 (2020)
Takasugi, T., Hanaoka, K., Sasaki, A., Ikeno, T., Komatsu, T., Ueno, T., Yamada, K., Urano, Y. Development of a platform for activatable fluorescent substrates of glucose transporters (GLUTs). Bioorg. Med. Chem. 27: 2122-2126 (2019)
Yamada, K. Aberrant Uptake of a Fluorescent L-Glucose Analogue (fLG) into Tumor Cells Expressing Malignant Phenotypes. Biol. Pharm. Bull. 41: 1508-1516 (2018)
Yamada, K., Sato, D., Nakamura, T., Amano, H., and Morimoto, Y. Unknown biological effects of L-glucose, ALA, and PUFA. J. Physiol. Sci. 67: 539-548 (2017)
Nagatomo, K., Suga S. Saitoh, M., Kogawa, M., Kobayashi, K., Yamamoto, Y., and Yamada, K. Dopamine D1 receptor immunoreactivity on fine processes of GFAP-positive astrocytes in the substantia nigra pars reticulata of adult mouse. Front. Neuroanat. 11: (2017). doi: 10.3389/fnana.2017.00003.
Shibasaki, K., Hosoi, N., Kaneko, R., Tominaga, M., and Yamada, K. Glycine release from astrocytes via functional reversal of GlyT1. J. Neurochem. 140: 395-403 (2017)
Masamoto, K., Hirase, H., Yamada, K., and Kanno, I. Neurovascular coupling-What next? Prog. Brain Res. 225: 269-272 (2016)
Yamada, K. “Vascular potassium channels in NVC” pp 63-73, In, New Horizons in Neurovascular Coupling, A Bridge Between Brain Circulation and Neuronal Plasticity. (Progress in Brain Research 225) 279 pages, Ed. by. Masamoto, K., Hirase, H., Yamada, K. Elsevier, Amsterdam (2016)
Yamada, K., Takahashi, S., Karube, F., Fujiyama, F., Kobayashi, K., Nishi, A., Momiyama, T. Neuronal circuits and physiological roles of the basal ganglia in terms of transmitters, receptors and related disorders. J. Physiol. Sci. 66: 435-446 (2016)
Otsuka, Y., Sasaki, A., Teshima, T., Yamada, K. Yamamoto, T. Syntheses of D-Glucose Derivatives Emitting Blue Fluorescence through Pd-Catalyzed C-N Coupling. Org. Lett. 18: 1338-1341 (2016)
Yokoyama, H., Sasaki, A., Yoshizawa, T., Kijima, H., Hakamada, K., Yamada, K. Imaging hamster model of bile duct cancer in vivo using fluorescent L-glucose derivatives. Human Cell 29: 111-121 (2016)
Sasaki, A., Nagatomo, K., Ono, K., Yamamoto, T., Otsuka, Y., Teshima, T., Yamada, K. Uptake of a fluorescent L-glucose derivative 2-NBDLG into three-dimensionally accumulating insulinoma cells in a phloretin-sensitive manner. Human Cell 29: 37-45 (2016)