1. Studies on biosynthesis and metabolism of proteoglycans, which organize the 
    extracellular matrix, and their roles in diseases.
2. Enzymatic reconstruction of glycosaminoglycans which posses physiological functions.
    Enzymatic conjugation of reconstructed glycosaminoglycans to peptides.
3. Studies on the relationship between the structure and the function of mucins.
4. Studies on the roles of the components of extracellular matrix. (Roles in tissue 
    organization, signal transduction, cell proliferation, cell differentiation, cell adhesion)