2002  2001    2000  1999    1998   1997    1996   1995

2002

Takagaki, K., Ishido K., Kakizaki, I., Iwafune, M., and Endo, M.
Carriers for enzymatic attachment of glycosaminoglycan chains to peptide
Biochem. Biophys. Res., Commun.,(2002) 293, 220-4.

Takagaki K., Iwafune M., Kakizaki I., Ishido K., Kato Y., and Endo M.
The cleavage of the xylosyl serine linkage between a core peptide and a glycosaminoglycan chain by cellulases. 
J. Biol. Chem.,(2002) 277, 18397-403.

Ishido,K., Takagaki, K., Iwafune, M., Yoshihara, S., Sasaki, M., and Endo, M.
Enzymatic attachment of glycosaminoglycan chain to peptide using the sugar chain transfer reaction with endo-beta-xylosidase.
J. Biol. Chem., (2002) 277, 11889-95.

Takagaki, K., Munakata, H., Kakizaki, I., Iwafne, M., Itabashi, T., and Endo, M.
Domain structure of chondroitin sulfate E octasaccharides binding to type V collagen.
J Biol Chem.(2002) 277, 8882-9.

Daidouji K., Takagaki K., Yoshihara S., Matsuya H., Sasaki M., and Endo M. 
Neoplastic changes in saccharide sequence of dermatan sulfate chains derived from human colon cancer. 
Dig Dis Sci. (2002) 47, 331-337

2001

Yukawa, M., Takagaki, K., Itabashi, T., Ueyama, K. , Harata, S., and Endo, M. 
Structural varieties of small proteoglycan in human spinal ligament. 
Connective Tissue Research (2001) 42 (3), 209社22

Majima, M., Takagaki, K., Sudo, S., Yoshihara, S., Kudo, Y., and Yamagishi, S.: 
Effect of proteoglycan on experimental colitis 
In New Developments in Glycomedicine, edited by Endo, M. , Harata, S., Saito, Y., Munakata, A., Sasaki, M., and Tsuchida, S., Elsevier Science B. V., Amsterdam, the Netherlands, (2001)  221社224

Takagaki, K., Kakizaki, I., Iwafune, M., Ishido, K. and Endo, M.: 
Enzymatic reconstruction of glycosaminoglycan oligosaccharides 
In New Developments in Glycomedicine, edited by Endo, M. , Harata, S., Saito, Y., Munakata, A., Sasaki, M., and Tsuchida, S., Elsevier Science B. V., Amsterdam, the Netherlands, (2001) 239社244

Endo, Y., Funahashi, M., Kakizaki, I., Takagaki, K., Endo, M., and Yokoyama, M.: 
Hyaluronan knockdown extracellular matrix of cultured human skin fibroblasts by use of 4-methylumbelliferone 
In New Developments in Glycomedicine, edited by Endo, M. , Harata, S., Saito, Y., Munakata, A., Sasaki, M., and Tsuchida, S., Elsevier Science B. V., Amsterdam, the Netherlands,  (2001) 265社268

Kakizaki, I., Takagaki, K., Endo, Y., Ikeya, H., Miyoshi, T., Nakane, A., Weigel, P. H. and Endo, M.
Effect of 4-methylumbelliferone on hyaluronan synthesis of Streptococcus equi FM100
In New Developments in Glycomedicine, edited by Endo, M. , Harata, S., Saito, Y., Munakata, A., Sasaki, M., and Tsuchida, S., Elsevier Science B. V., Amsterdam, the Netherlands, (2001) 269社272

Kukidome, J., Kakizaki, I., Takagaki, K., Matsuki, A., Munakata, A., and Endo, M. 
The mechanism of cell death in human cultured colon adenocarcinoma cell line COLO 201 induced by b-D-N-acetylglucosaminyl-p-nitrophenol
Tohoku J. Ex.p Med. (2001) 194, 23社34

Matsuya, H., Takagaki, K., Yoshihara, S., Ishido, K., Sasaki, M., and Endo, M.
Changes in glycosaminoglycan, galactosyltransferase-I, and sialyltransferase during rat liver regeneration.
Tohoku J. Exp. Med. (2001) 193, 187社195

Higuchi, T., Tamura, S., Tanaka, K., Takagaki, K., Saito, Y., and Endo, M.
Effects of ATP on regulation of galactosyl-transferase-I activity responsible for synthesis of the linkage region between the core protein and glycosaminoglycan chains of proteoglycans.
Biochem. Cell Biol. (2001) 79, 159-164

Kukidome, J., Kakizaki, I., Takagaki, K., Matsuki, A., Munakata, A., Endo, M.
Studies on sugar chain elongation in cultured human colon adenocarcinoma cells using 4-methylumbelliferyl glycoside derivatives and p-nitrophenyl glycoside derivatives as artificial primers.
Hirosaki Med. J. (2001) 52, 59社65

2000


Takagaki, K., Munakata, H., Kakizaki, I., Majima, M., Endo, M.
Enzymatic reconstruction of dermatan sulfate.
Biochem. Biophys. Res. Commun. (2000) 270 (2), 588社593

Takagaki, K., Munakata, H., Majima, M., Kakizaki, I., Endo, M.
Chimeric glycosaminoglycan oligosaccharides synthesized by enzymatic reconstruction and their use in substrate specificity determination of Streptococcus hyaluronidase.
J. Biochem. (Tokyo) (2000) 127 (4), 695社702

Matsuki, A., Takagaki, K., Kukidome, J., Endo, M., and Munakata, A.
Analysis of p-nitrophenyl N-Acetyl-a-D-galactosaminide-induced oligosaccharides produced by the cultured human colon adenocarcinoma cell, DLD-1.
Hirosaki Med. J. (2000) 52, 1社9 

Takagaki, K., and Ishido, K.
Synthesis of chondroitin sulfate oligosaccharides using enzymatic reconstruction.
Trends Glycosci. Glyc. (2000) 12 (67), 295社306 

Endo, Y., Takagaki, K., Takahashi, G., Kakizaki, I., Funahashi, M., Yokoyama, M., and Endo, M.
Formation of hyaluronic acid-knock-down extracellular matrix using 4-methylumbelliferone.
In Progress in Transplantation, edited by Munakata, A. Elsevier Science B. V., Amsterdam, the Netherlands, (2000) 1社7

1999


Takagaki, K., Munakata, H., Majima, M., and Endo, M.
Enzymatic reconstruction of a hybrid glycosaminoglycan containing 6-sulfated, 4-sulfated, and unsulfated N-acetylgalactosamine.
Biochem. Biophys. Res. Commun. (1999) 258, 741社744 

Munakata, H., Takagaki, K., Majima, M, and Endo, M.
Interaction between collagens and glycosaminoglycans investigated using a surface plasmon resonance biosensor.
Glycobiology (1999) 9 (10), 1023社1027 

Takagaki, K., Kakizaki, I., and Endo, M
Development of an enzymatic synthesis method for chimeric glycosaminoglycans.
Hirosaki Med. J. (1999) 51 (Suppl.), S49社S53

1998


Takagaki, K., Munakata, H., Nakamura, W., Matsuya, H., Majima, M., and Endo, M.
Ion-spray mass spectrometry for identification of the nonreducing terminal sugar of glycosaminoglycan.
Glycobiology (1998) 8, 719社724

Takagaki, K., Tazawa, T., Munakata, H., Nakamura, T., and Endo, M.
Characterization of ｦﾂ-D-xyloside-initiated glycosaminoglycan synthesized by human skin fibroblasts in the presence of tunicamycin.
Glycoconjugate J. (1998), 15, 483社489

Tazawa, T., Takagaki, K., Matsuya, H., Nakamura, T., Sasaki, M., and Endo, M.
A novel 4-methylumbelliferyl-ｦﾂ-D-xyloside derivative, sulfate-O-3-xylosyl-ｦﾂ1-(4-methylumbelliferone), isolated from culture medium of human skin fibroblasts, and its role in 4-methylumbelliferone-initiated glycosaminoglycan biosynthesis.
Glycobiology (1998) 8, 879社884

Ono, A., Harata, S., Takagaki, K., and Endo, M.
Proteoglycans in the nucleus pulposus of canine intervertebral disc after chondroitinase ABC treatment.
J. Spin. Disord. (1998) 11, 253社260

1997


Tanaka, K., Nakamura, T., Takagaki, K., Funahashi, M., Saito, Y., and Endo, M.
Regulation of hyaluronate metabolism by progesterone in cultured skin fibroblasts from the human uterine cervix.
FEBS Lett. (1997) 402, 223社226

Takagaki, K., Tazawa, T., Munakata, H., Nakamura, T., and Endo, M.
Effect of monensin on the synthesis of ｦﾂ-D-xyloside-induced glycosaminoglycan and its linkage region oligosaccharides in human skin fibroblasts. 
J. Biochem. (1997) 122, 1129社1132

Yasukochi, T., Fukase, K., Suda, Y., Takagaki, K., Endo, M., and Kusumoto, S.
Enzymatic synthesis of 4-methylumbelliferyl glycosides of trisaccharide, and core tetrasaccharide, Gal(ｦﾂ1-3)Gal(ｦﾂ1-4)Xyl and GlcA(ｦﾂ1-3)Gal(ｦﾂ1-3)Gal(ｦﾂ1-4)Xyl, corresponding to the linkage region of proteoglycans.
Bull. Chem. Soc. Jpn. (1997) 70, 2719社2725 

Nakamura, T., Funahashi, Takagaki, K., Munakata, H., Tanaka, K,, Saito, Y., and Endo, M.
Effect of 4-methylumbelliferone on cell-free synthesis of hyaluronic acid.
Biochem. Mol. Biol. Int. (1997) 43, 263社268 

1996


Takagaki, K., Nakamura, T., Shibata, S., Higuchi, T., and Endo, M.
Characterization and biological significance of sialylｦﾁ2-3galactosylｦﾂ1-4xylosylｦﾂ1-(4-methylumbelliferone) synthesized in cultured human skin fibroblasts.
 J. Biochem.  (1996) 119, 697社702

Saitoh, H., Takagaki, K., Nakamura, T., Munakata, A., Yoshida, Y., and Endo, M. 
Characterization of mucin in whole-gut lavage fluid obtained from patients with inflammatory bowel disease.
Dig. Dis. Sci. (1996) 41, 1768社1774 

Nakamura, T., Takagaki, K., and Endo, M.
New hyaluronan-degrading enzymes.
Connective Tissue (1996) 28, 15社19 

1995


Saitoh, H., Takagaki, K., Majima, M., Nakamura, T., Matsuki, A., Kasai, M., Narita, H., and Endo, M.
Enzymic reconstruction of glycosaminoglycan oligosaccharide chain using the transglycosylation reaction of bovine testicular hyaluronidase.
J. Biol. Chem. (1995) 270, 3741社3747 

Nakamura, T., Takagaki, K., Shibata, S., Tanaka, K., Higuchi, T., and Endo, M.
Hyaluronic acid-defficient extracellular matrix induced by addition of 
4-methylumbelliferone to the medium of cultured human fibroblasts.
Biochem. Biophys. Res. Commun.(1995) 208, 470社475 

Yoshihara, S., Matsue, H., Sasaki, M., Shibata, S., Konn, M., Fukuzawa, A., and Endo, M.
Chemical structure of the carbohydrate moiety of fucose-rich glycopeptides from human pancreatic juice. 
Int. J. Pancreatol.(1995) 17, 181社187 

Shibata, S., Takagaki, K., Nakamura, T., Izumi, J., Kojima, K., Kato, I., and Endo, M. 
HNK-1-reactive novel oligosaccharide, sulfate-O-3GlcAｦﾂ1-4Xylｦﾂ1-(4-methylumbelliferone), synthesized by cultured human skin fibroblasts.
J. Biol. Chem. (1995) 270, 13794社13798 

Endo, M., Takagaki, K., Nakamura, T., and Majima, M.
Synthesis of recombinant glycosaminoglycan chains using the transglycosylation of endo-type glycosidases.
Glycoconjugate J. (1995) 12, 483 

Narita, H., Takeda, Y., Takagaki, K., Nakamura, T., Harata, S., and Endo, M.
Identification of glycosaminoglycans using high-performance liquid chromatography on a hydroxyapatite column.
Anal. Biochem. (1995) 232, 133社136

Takagaki, K., Nakamura, T., and Endo, M.
Reconstruction of glycosaminoglycans using the transglycosylation reaction of testicular hyaluronidase.
Connective Tissue (1995) 27, 207社211