ƒz[ƒ€@>@Œ¤‹†‹ÆÑ@>@2012”NE2013”NE2014”NE2015”NE2016”NE2017”N@Œ¤‹†‹ÆÑ

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2017”N@Œ¤‹†‹ÆÑ

y ˜_ •¶ z

  • Kasai S, Richardson M. J. E., Torii S, Yasumoto K, Shima H, Igarashi K, Itoh K, Sogawa K, Murayama K. Increase in proapoptotic activity of inhibitory PAS domain protein via phosphorylation by MK2. FEBS J 2017;284:4115-4127.
  • K.Tatara Y, Suto S, Itoh K. Novel roles of glycosaminoglycans in the degradation of type I collagen by cathepsin. Glycobiology.2017;27:1089-1098.
  • Sakai E, Morita M, Ohuchi M, Kido MA, Fukuma Y, Nishishita K, Okamoto K, Itoh K, Yamamoto M, Tsukuba T. Effects of deficiency of Kelch-like ECH-associated protein 1 on skeletal organization: a mechanism for diminished nuclear factor of activated T cells cytoplasmic 1 during osteoclastogenesis. FASEB J 2017;31:4011-4022.
  • ŽO‘ºƒ³AˆÉ“ŒŒ’DNrf2ƒVƒXƒeƒ€‚É‚æ‚鐶‘Ì–hŒä‰ž“šD—Տ°–ƉuEƒAƒŒƒ‹ƒM[‰ÈC2017;67(6):642-648.
  • ŽR›½”Ž–¢AEngler Mate JanosAˆÉ“ŒŒ’. Nrf2‚̍R˜V‰»ˆöŽq‚Æ‚µ‚Ä‚Ì–ðŠ„.@‘æ37‰ñ‘‰ïƒVƒ“ƒ|ƒWƒEƒ€‚Ru˜V‰»‚ƏzŠÂ§ŒävC2017;21-33.

2016”N@Œ¤‹†‹ÆÑ

y ˜_ •¶ z

  • Tanji K, Miki Y, Maruyama A, Mori F, Mimura J, Itoh K, Kamitani T, Wakabayashi K. The role of NUB1 in ƒ¿-synuclein degradation in Lewy body disease model mice. Biochem Biophys Res Commun. 2016;470:635-642.
  • Liu PY, Sokolowski N, Guo ST, Siddiqi F, Atmadibrata B, Telfer TJ, Sun Y, Zhang L, Yu D, Mccarroll J, Liu B, Yang RH, Guo XY, Tee AE, Itoh K, Wang J, Kavallaris M, Haber M, Norris MD, Cheung BB, Byrne JA, Ziegler DS, Marshall GM, Dinger ME, Codd R, Zhang XD, Liu T. The BET bromodomain inhibitor exerts the most potent synergistic anticancer effects in combination with quinone-containing compounds and anti-microtubule drugs. Oncotarget.2016;7:79217-79232.

2015”N@Œ¤‹†‹ÆÑ

y ˜_ •¶ z

  • Tanji K, Odagiri S, Miki Y, Maruyama A, Nikaido Y, Mimura J, Mori F, Warabi E, Yanagawa T, Ueno S, Itoh K, Wakabayashi K. p62 Deficiency Enhances ƒ¿-Synuclein Pathology in Mice. Brain Pathol. 2015;25(5):552-564.
  • Meng P, Yoshida H, Tanji K, Matsumiya T, Xing F, Hayakari R, Wang L, Tsuruga K, Tanaka H, Mimura J, Kosaka K, Itoh K, Takahashi I, Kawaguchi S, Imaizumi T. Carnosic acid attenuates apoptosis induced by amyloid-ƒÀ 1-42 or 1-43 in SH-SY5Y human neuroblastoma cells. Neurosci Res. 2015;94(1):1-9.
  • Itoh K, Ye P, Matsumiya T, Tanji K, Ozaki T. Emerging functional cross-talk between the Keap1-Nrf2 system and mitochondria. J Clin Biochem Nutr. 2015;56(2):91-97.
  • Yamazaki H, Tanji K, Wakabayashi K, Matsuura S, Itoh K. Role of the Keap1/Nrf2 pathway in neurodegenerative diseases. Pathol.Int. 2015;65(5):210-219.
  • Mimura J, Itoh K. Role of Nrf2 in the pathogenesis of atherosclerosis. Free Radic Biol Med. 2015;88(Pt B):221-232.
  • Tanji K, Miki Y, Maruyama A, Mimura J, Matsumiya T, Mori F, Imaizumi T, Itoh K, Wakabayashi K. Trehalose intake induces chaperone molecules along with autophagy in a mouse model of Lewy body disease. Biochem Biophys Res Commun. 2015;465(4):746-752.
  • Maruyama A, Itoh K. Role of the Keap1-Nrf2 pathway in protection against ionizing radiation. Fukushima Nuclear Accident: Global Implications, Long-Term Health Effects, and Ecological Consequences. Nova.

2014”N@Œ¤‹†‹ÆÑ

y ˜_ •¶ z

  • Yageta Y, Ishii Y, Morishima Y, Ano S, Ohtsuka S, Matsuyama M, Takeuchi K, Itoh K, Yamamoto M, Hizawa N. Carbocisteine Reduces Viral-Induced Pulmonary Inflammation in Mice Exposed to Cigarette Smoke. Am J Respir Cell Mol Biol. 2014;50(5):963-73.
  • Tanji K, Miki Y, Ozaki T, Maruyama A, Yoshida H, Mimura J, Matsumiya T, Mori F, Imaizumi T, Itoh K, Kakita A, Takahashi H, Wakabayashi K. Phosphorylation of serine 349 of p62 in Alzheimerfs disease brain. Acta Neuropathologica Communications 2014;2:50.
  • Ye P, Mimura J, Okada T, Sato H, Liu T, Maruyama A, Ohyama C, Itoh K. Nrf2- and ATF4-dependent up-regulation of xCT modulates the sensitivity of T24 bladder carcinoma cells to proteasome inhibition. Mol Cell Biol. 2014;34(18):3421-34.
  • Maruyama A, Mimura J, Itoh K. Non-coding RNA derived from the region adjacent to the human HO-1 E2 enhancer selectively regulates HO-1 gene induction by modulating Pol II binding. Nucleic Acids Res. 2014;42(22):13599[614.

2013”N@Œ¤‹†‹ÆÑ

y ˜_ •¶ z

  • Tanji K, Maruyama A, Odagiri S, Mori F, Itoh K, Kakita A, Takahashi H, Wakabayashi K. Keap1 is localized in neuronal and glial cytoplasmic inclusions in various neurodegenerative diseases. J Neuropathol Exp Neurol. 2013;72(1):18-28.
  • Meng P, Yoshida H, Matsumiya T, Imaizumi T, Tanji K, Xing F, Hayakari R, Dempoya J, Tatsuta T, Aizawa-Yoshihiro T, Mimura J, Kosaka K, Itoh K, Satoh K. Carnosic acid suppresses the production of amyloid-b 1-42 by inducing the metalloprotease gene TACE/ADAM17 in SH-SY5Y human neuroblastoma cells. Neurosci Res. 2013;75(2):94-102.
  • Maruyama A, Mimura J, Harada N, Itoh K. Nrf2 activation is associated with Z-DNA formation in the human HO-1 promoter. Nucleic Acids Res. 2013;41(10):5223-34.
  • Okita Y, Kamoshida A, Suzuki H, Itoh K, Motohashi H, Igarashi K, Yamamoto M, Ogami T, Koinuma D, Kato M. Transforming Growth Factor-ƒÀ Induces Transcription Factors MafK and Bach1 to Suppress Expression of the Heme Oxygenase-1 Gene. J Biol Chem. 2013;288(28):20658-67.
  • Yoshida H, Meng P, Matsumiya T, Tanji K, Hayakari R, Xing F, Wang L, Tsuruga K, Tanaka H, Mimura J, Kosaka K, Itoh K, Takahashi I, Imaizumi T. Carnosic acid suppresses the production of amyloid-ƒÀ 1-42 and 1-43 by inducing an ƒ¿-secretase TACE/ADAM17 in U373MG human astrocytoma cells. Neurosci Res. 2013;S0168-0102(13)00261-7.

2012”N@Œ¤‹†‹ÆÑ

y ˜_ •¶ z

  • Harada N, Ito K, Hosoya T, Mimura J, Mruyama A, Noguchi N, Yagami K, Morito N, Takahashi S, Maher JM, Yamamoto M, Itoh K. Nrf2 in the bone marrow-derived cells positively contributes to the advanced stage of atherosclerotic plaque formation. Free Radic. Biol. Med. 2012;53(12),2256-2262.
  • ˆÉ“ŒŒ’A‰Ú–¼^sA×–E‚ÌŽ_‰»ƒXƒgƒŒƒX‘ϐ«‚ÉŠÖ‚í‚éƒVƒOƒiƒ‹“`’BŒn---Nrf2/Keap1ƒVƒOƒiƒŠƒ“ƒO‚ÆŽ©ŒÈ–h‰q‹@”\A‰»Šw‚Ɛ¶•¨A2012;50(6),423-429
  • Yamadori T, Ishii Y, Homma S, Morishima Y, Kurishima K, Itoh K, Yamamoto M, Minami Y, Noguchi M, Hizawa N. Molecular mechanisms for the regulation of Nrf2-mediated cell proliferation in non-small-cell lung cancers. Oncogene. 2012;31(45),4768-4777.
  • Okada K, Warabi E, Sugimoto H, Horie M, Tokushige K, Ueda T, Harada N, Taguchi K, Hashimoto E, Itoh K, Ishii T, Utsunomiya H, Yamamoto M, Shoda J. Nrf2 inhibits hepatic iron accumulation and counteracts oxidative stress-induced liver injury in nutritional steatohepatitis. J Gastroenterol. 2012
  • Hanada N, Takahata T, Zhou Q, Ye X, Sun R, Itoh J, Ishiguro A, Kijima H, Mimura J, Itoh K, Fukuda S, Saijo Y. Methylation of the KEAP1 gene promoter region in human colorectal cancer. BMC Cancer. 2012;12(1):66.