iChIP

iChIP (insertional ChIP) is the technology to isolate specific DNA regions for identification of their associated molecules by insertion of recognition sequences of an exogenous DNA-binding molecule into the target DNA regions followed by affinity purification with the exogenous DNA-binding molecule. The technology is covered by our patents (US 8415098, JP 5413924).

enChIP

enChIP (engineered DNA-binding molecule-mediated ChIP) is the technology to isolate specific DNA regions for identification of their associated molecules using engineered DNA-binding molecules recognizing the target DNA regions. Engineered DNA-binding molecules include the CRISPR complexes consisting of a catalytically inactive form of Cas9 protein (dCas9) and guide RNA (gRNA), transcription-activator-like effector (TAL or TALE), and others. The technology is covered by our patents (JP 5954808, EP 2963113, US 11466306).

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