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Endocrinology and Metabolism内分泌代謝内科学講座
Staffs
- Professor: Yukihiro Fujita
- Associate Professor: Shinobu Takayasu, Miyuki Yanagimachi
- Lecturer: Jutaro Tanabe
- Lecturer (Hospital affiliation): Yuki Matsuhashi, Kota Matsuki
- Assistant Professor: Tsuyoshi Yanagimachi, Shingo Murasawa, Yuki Nakada, Yuko Asari, Sho Osonoi, Yuki Nishiya, Kiho Hamaura
- Research Associate: Mari Usutani
Educational program
- 1. Trainees are requested to have fruitful expertise as a clinical expert and/or an established researcher who can pursue new findings from clinical cases. Trainees can learn methods of clinical statistics and data analysis through big cohort, observational, or intentional studies.
- 2. Trainees can learn experimental techniques in vitro and in vivo (animal experiments, tissue culturing, molecular biology, gene expression analysis, western blotting, immunohistochemistry, radioisotope experiments, and assays (eg. ELISA)) to gain new insights into diabetes, metabolic and endocrine diseases.
- 3. Trainees are expected to publish case reports or original articles from their experienced cases or basic research with vigorous investigations.
- 4. Trainees are encouraged to expand their research in domestic and international outstanding laboratories.
Research program
＜Basic Research＞
- 1. Measurement of cholesterol efflux by HDL and identification of its regulating factors.
- 2. Secretion and physiological actions of incretin, especially short-form GIP.
- 3. Physiological effects and biological activities of oxyntomodulin, a glucagon-related peptide.
- 4. Ketone bodies in the small intestine, nutrient signaling and systemic metabolic regulation
- 5. Biology of proglucagon-producing cells.
- 6. Regulatory mechanism of pro-opiomelanocortin gene expression in ACTH-producing cells
- 7. Mechanistic analysis in glucocorticoid receptor gene mutations.
＜Clinical Research＞
- 1. Changes in pancreatic function and nutritional status after pancreatectomy.
- 2. Investigation of appropriate blood glucose management for pancreatogenic diabetes mellitus (Type 3B diabetes).
- 3. Relationship between diabetes treatment and resting energy metabolism.
- 4. The relationship between periodontal disease and diabetes mellitus.
- 5. Clinical evaluation of diabetic neuropathy using simple testing devices.
- 6. Investigation of early diagnosis of pituitary dysfunction by immune checkpoint inhibitors.
- 7. Development of diagnostic methods for subclinical hypopituitarism.
- 8. Clinical differentiation between ACTH-dependent Cushing syndrome and pseudo-Cushing syndrome.