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Institute for Animal Experimentation動物実験施設
Staffs
- Assistant professor: Kouji Narita
Introduction of facility
The Institute for Animal Experimentation is a research-supporting organization and all animal experiments at the Graduate School of Medicine are primarily conducted at this facility. The facility provides advanced research and education using high-quality laboratory animals. The animal rooms are maintained at room temperature (23 ± 3 °C) and humidity (50 ± 10%) throughout the year to minimize the environmental effects on the outcome of the animal experiments. Approximately 10 staff members attend to the needs of researchers, including a full-time instructor and a Level 2 experimental animal technologist.
As part of our research support services, we prepare cryopreserved sperm from genetically modified mice and generate animals through in vitro fertilization using thawed sperm. To protect genetically engineered animals from infectious agents, This facility is equipped with individually ventilated cage (IVC) systems. In addition, specialized housing and laboratory spaces have been established to support xenotransplantation studies using severely immunodeficient mouse strains such as NOG mice. This facility is accessible at all times. Besides a large shared experimental space accessible to all researchers, we offer both dedicated laboratories and specialized rooms for infectious disease and hazardous substance experiments. This facility provides a safe and well-organized environment that supports efficient experimental work. Utilizing these resources, a wide range of studies are actively conducted from both basic and clinical perspectives. These include xenotransplantation experiments, investigations into disease mechanisms using animal models for diabetes and hypertension, and studies on the interactions between infectious diseases and cytokine responses.